Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677275 | 0.84 | MAPT (0.73) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL5004832 | 0.81 | ALDH1A1 (0.69) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL22291692 | 0.81 | MAPT (0.69) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16095485 | 0.81 | ALDH1A1 (0.51) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL10628038 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL2774063 | 0.80 | MAPT (1.00) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4899731 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL16095273 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL607025 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL11819120 | 0.80 | MAPT (0.67) | MAPTALDH1A1LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |