Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.39 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6736896 | 0.89 | POLB (0.47) | POLBGAAIMPDH2IMPDH1TSHR | |
| SCHEMBL7672587 | 0.80 | GAA (0.41) | POLBGAAIMPDH2IMPDH1TSHR | |
| SCHEMBL18125262 | 0.80 | GAA (0.41) | POLBGAAIMPDH2IMPDH1TSHR | |
| SCHEMBL16959666 | 0.80 | KDM4E (0.33) | KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL16954482 | 0.79 | GAA (0.35) | GAATSHRMAPTARKDM4E | |
| SCHEMBL10070159 | 0.78 | TSHR (0.61) | POLBGAAIMPDH2IMPDH1TSHR | |
| SCHEMBL30934831 | 0.78 | POLB (0.50) | POLBGAAIMPDH2IMPDH1AR | |
| SCHEMBL338999 | 0.78 | POLB (0.50) | POLBGAAIMPDH2IMPDH1AR | |
| SCHEMBL16958921 | 0.78 | TSHR (0.40) | TSHRARKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6944651 | 0.78 | SMN1; SMN2 (0.45) | GAAMAPTKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |