Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961103 | 0.85 | NPSR1 (0.39) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL16959448 | 0.83 | DRD1 (0.34) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL16958856 | 0.83 | KCNH2 (0.33) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL16960319 | 0.83 | ALDH1A1 (0.39) | SMN1; SMN2KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL16954028 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2CA12CA1CA2CA4 | |
| SCHEMBL16958617 | 0.82 | KCNK3 (0.36) | SMN1; SMN2NFE2L2KDM4EALDH1A1MEN1 | |
| SCHEMBL16950875 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1LMNAALOX15MEN1 | |
| SCHEMBL16951404 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPK1MAPTALDH1A1LMNA | |
| SCHEMBL2902141 | 0.80 | CA1 (0.55) | CA12CA1CA2CA4CA7 | |
| SCHEMBL338999 | 0.79 | POLB (0.50) | SMN1; SMN2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003519628-A | — | — | 2003-06-24 | — | — | JP | claimed |
| EP-1257558-A1 | METHODS FOR SYNTHESIS OF ALPHA-D-GAL (1- 3) GAL-CONTAINING OLIGOSACCHARIDES | Alchemia Pty Ltd (AU) | 2002-11-20 | — | — | EP | claimed |
| WO-2001051499-A1 | METHODS FOR SYNTHESIS OF α-D-GAL (1→3) GAL-CONTAINING OLIGOSACCHARIDES | ALCHEMIA PTY LTD (AU) | 2001-07-19 | — | — | WO | claimed |
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |