Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16950581 | 0.84 | CES2 (0.48) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16952029 | 0.83 | CES2 (0.52) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16958816 | 0.83 | CES2 (0.52) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16959379 | 0.82 | CES2 (0.50) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16961117 | 0.82 | CES2 (0.50) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16957361 | 0.81 | CES2 (0.46) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16955185 | 0.79 | CES2 (0.52) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL16958839 | 0.79 | CES2 (0.47) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL8761571 | 0.78 | CES2 (0.60) | PTGS1PTGS2CES2CES1PARP1 | |
| SCHEMBL633161 | 0.78 | CES2 (0.61) | PTGS1PTGS2CES2CES1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |