Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961779 | 0.84 | TDP1 (0.35) | NOTUM | |
| SCHEMBL16957949 | 0.84 | HCRTR1 (0.33) | HCRTR1HCRTR2CHRM4CHRM1HTR1A | |
| SCHEMBL16955791 | 0.80 | HTR1D (0.32) | HCRTR1HCRTR2CHRM4CHRM1HTR1A | |
| SCHEMBL16952095 | 0.79 | ALDH1A1 (0.38) | HCRTR1HCRTR2ALDH1A1KDM4E | |
| SCHEMBL16958908 | 0.78 | HCRTR1 (0.32) | HCRTR1HCRTR2NOTUM | |
| SCHEMBL16957690 | 0.78 | KDM4E (0.38) | SLC6A4ALDH1A1KDM4E | |
| SCHEMBL16960667 | 0.78 | HCRTR1 (0.40) | HCRTR1ALDH1A1KDM4E | |
| SCHEMBL16952964 | 0.78 | NOTUM (0.33) | HCRTR1HCRTR2NOTUM | |
| SCHEMBL16952841 | 0.78 | KDM4E (0.39) | HCRTR1ALDH1A1KDM4E | |
| SCHEMBL16951242 | 0.78 | KDM4E (0.38) | SLC6A2SLC6A4SLC6A3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |