Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 5/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | VEGFA | P15692 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16954818 | 0.83 | ALK (0.39) | AR | |
| SCHEMBL16952358 | 0.83 | PDE4B (0.39) | SLC22A12PDE4BCCR5CYP11B1CYP11B2 | |
| SCHEMBL10164859 | 0.80 | SLC22A12 (0.43) | SLC22A12PDE4BAR | |
| SCHEMBL16951588 | 0.79 | AR (0.47) | PDE4BAR | |
| SCHEMBL16955678 | 0.79 | SLC22A12 (0.36) | SLC22A12PDE4BCYP11B1CYP11B2TDP2 | |
| SCHEMBL16951571 | 0.79 | HRH4 (0.36) | EPAS1TDP2ARVEGFA | |
| SCHEMBL16952820 | 0.77 | MAPT (0.38) | — | |
| SCHEMBL2448493 | 0.77 | USP30 (0.41) | SLC22A12CYP11B1CYP11B2ARGRIN1 | |
| SCHEMBL16957727 | 0.77 | SLC22A12 (0.37) | SLC22A12PDE4BCYP11B1CYP11B2AR | |
| SCHEMBL16177839 | 0.76 | CA12 (0.38) | SLC22A12PDE4BCYP11B1CYP11B2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |