Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959958 | 0.83 | IRAK4 (0.38) | AR | |
| SCHEMBL16957729 | 0.83 | EPAS1 (0.35) | PDE4BCCR5SLC22A12CYP11B1CYP11B2 | |
| SCHEMBL10164859 | 0.80 | SLC22A12 (0.43) | PDE4BSLC22A12AR | |
| SCHEMBL16955355 | 0.79 | AR (0.47) | PDE4BAR | |
| SCHEMBL16177839 | 0.79 | CA12 (0.38) | PDE4BSLC22A12CYP11B1CYP11B2PTGDR2 | |
| SCHEMBL16955763 | 0.79 | HRH4 (0.36) | CCR5TDP2PTGDR2 | |
| SCHEMBL2448493 | 0.77 | USP30 (0.41) | SLC22A12CYP11B1CYP11B2AR | |
| SCHEMBL16958137 | 0.77 | MAPT (0.40) | PDE4B | |
| SCHEMBL14150477 | 0.76 | KDM4E (0.39) | PDE4BSLC22A12AR | |
| SCHEMBL22658071 | 0.76 | NR3C1 (0.39) | SLC22A12CYP11B1CYP11B2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |