Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16956041 | 0.89 | CNR1 (0.45) | AHRCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL16954683 | 0.89 | CNR1 (0.42) | AHRCHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL21300605 | 0.87 | CNR1 (0.50) | AHRALDH1A1LMNASMN1; SMN2CNR1 | |
| SCHEMBL13306813 | 0.85 | NR1I2 (0.37) | ALDH1A1LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL16952179 | 0.84 | AHR (0.39) | AHRSMN1; SMN2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL16957170 | 0.84 | ESR1 (0.38) | AHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16960271 | 0.83 | AHR (0.43) | AHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16953268 | 0.83 | AHR (0.49) | AHRALDH1A1SMN1; SMN2CHRNB2CHRNB4 | |
| SCHEMBL5251054 | 0.82 | LTA4H (0.48) | AHRALDH1A1LMNAMAPTHPGD | |
| SCHEMBL16951599 | 0.81 | AHR (0.44) | AHRALDH1A1CHRNB2CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |