Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 5/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16953425 | 0.86 | CHRM2 (0.35) | PTGS2CHRM2CHRM1CHRM3CETP | |
| SCHEMBL16954729 | 0.85 | PTGS2 (0.38) | PTGS2CA1CA2CA9CHRM2 | |
| SCHEMBL16951086 | 0.81 | PTGS2 (0.53) | PTGS2CA1CA2CA9NPC1 | |
| SCHEMBL16956137 | 0.80 | NPC1 (0.36) | PTGS2NPC1HPGDMAPK1HTT | |
| SCHEMBL16958219 | 0.80 | CNR1 (0.40) | PTGS2CA1CA2CA9CHRM2 | |
| SCHEMBL16956041 | 0.80 | CNR1 (0.45) | PTGS2CA1CA2CA9CNR1 | |
| SCHEMBL16956267 | 0.79 | PTGS2 (0.35) | PTGS2CA1CA2CA9NPC1 | |
| SCHEMBL16960454 | 0.79 | CHRM2 (0.34) | PTGS2CA1CA2CA9CHRM2 | |
| SCHEMBL27377051 | 0.79 | GRIN2B (0.33) | CHRM2CHRM1CHRM3CETP | |
| SCHEMBL1780397 | 0.79 | HPGD (0.45) | PTGS2CA1CA2NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |