Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958459 | 0.88 | TTR (0.40) | TTRALBALDH1A1CYP2A6MAPT | |
| SCHEMBL16954701 | 0.84 | TTR (0.34) | TTRALBALDH1A1CYP2A6MAPT | |
| SCHEMBL16955392 | 0.80 | TTR (0.40) | TTRALBALDH1A1CYP2A6MAPT | |
| SCHEMBL16960523 | 0.80 | TTR (0.38) | TTRALBALDH1A1CYP2A6MAPT | |
| SCHEMBL16951138 | 0.80 | TTR (0.42) | TTRALBALDH1A1MAPTMEN1 | |
| SCHEMBL16958193 | 0.80 | — | — | |
| SCHEMBL16955083 | 0.80 | TPMT (0.44) | ALDH1A1 | |
| SCHEMBL16953129 | 0.79 | CYP2A6 (0.41) | TTRALBALDH1A1CYP2A6MAPT | |
| SCHEMBL16951966 | 0.79 | PDE4A (0.38) | ALDH1A1MAPT | |
| SCHEMBL16953825 | 0.77 | FFAR4 (0.34) | TTRALBALDH1A1MAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |