Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16952485 | 0.87 | ALDH1A1 (0.50) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL16958459 | 0.85 | TTR (0.40) | ALDH1A1MAPT | |
| SCHEMBL16954235 | 0.83 | MAPT (0.40) | ALDH1A1MAPTGAA | |
| SCHEMBL16960693 | 0.82 | MAPT (0.42) | ALDH1A1MAPTKDM4E | |
| SCHEMBL16961693 | 0.82 | ALDH1A1 (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL16953826 | 0.80 | MAPT (0.37) | ALDH1A1MAPT | |
| SCHEMBL202404 | 0.79 | ALDH1A1 (0.61) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL16959079 | 0.79 | TTR (0.35) | ALDH1A1MAPT | |
| SCHEMBL16951138 | 0.77 | TTR (0.42) | ALDH1A1MAPT | |
| SCHEMBL16960523 | 0.77 | TTR (0.38) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |