Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958672 | 0.87 | PLA2G2A (0.46) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL16960378 | 0.86 | PLA2G2A (0.43) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL16958988 | 0.84 | PLA2G2A (0.44) | PLA2G2ARAB9ALTA4HNR5A1GAA | |
| SCHEMBL16960368 | 0.83 | PLA2G2A (0.43) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL16960479 | 0.83 | PLA2G2A (0.43) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL2666319 | 0.81 | PLA2G2A (0.69) | PLA2G2AKMT2ATP53TSHRPLA2G4B | |
| SCHEMBL3784498 | 0.80 | MAPT (0.53) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL8297095 | 0.80 | MAPT (0.59) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL16953340 | 0.80 | PLA2G2A (0.41) | PLA2G2ARAB9ANPC1SMN1; SMN2HSD17B10 | |
| SCHEMBL16957061 | 0.77 | MAOB (0.36) | SMN1; SMN2MAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |