Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27857027 | 0.81 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2TYRCA2POLB | |
| SCHEMBL20876091 | 0.79 | AR (0.38) | SMN1; SMN2CYP1A2CYP2A6KDM4EMAPT | |
| SCHEMBL17594923 | 0.77 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2TYRCA2POLB | |
| SCHEMBL2146967 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TYRCA2TSHR | |
| SCHEMBL114856 | 0.75 | TDP1 (0.44) | ALDH1A1SMN1; SMN2TYRCA2POLB | |
| SCHEMBL16954376 | 0.74 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2TYRTSHRCYP1A2 | |
| SCHEMBL16953842 | 0.74 | PTGDR2 (0.39) | ALDH1A1SMN1; SMN2TYRCA2CYP1A2 | |
| SCHEMBL16950909 | 0.74 | PTGS1 (0.39) | ALDH1A1SMN1; SMN2TYRCA2PTGS1 | |
| SCHEMBL180815 | 0.73 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2TYRCA2POLB | |
| SCHEMBL396022 | 0.73 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2TYRCA2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-1208383-C | Nano-grade inorganics filled synthetic resin micropore material | SHANGHAI GENIUS ADVANCED MAT (CN) | 2005-06-29 | — | — | CN | disclosed |
| CN-1400239-A | Nano-grade inorganics filled synthetic resin micropore material | SHANGHAI JIESHIJIE NEW MATERIA (CN) | 2003-03-05 | — | — | CN | disclosed |