Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050524 | 0.75 | KDM4C (0.54) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4640764 | 0.74 | HRH3 (0.49) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31186652 | 0.74 | KDM4C (0.46) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL30716140 | 0.73 | KDM4C (0.44) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL26841338 | 0.73 | KDM4C (0.44) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL9858541 | 0.72 | KDM4C (0.47) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL106859 | 0.71 | KDM4E (0.41) | KDM4EALDH1A1LMNATP53ALOX15 | |
| SCHEMBL258369 | 0.68 | KDM4C (0.51) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14825830 | 0.67 | ATM (0.53) | MEN1KMT2ALMNAHTTCHRM2 | |
| Hydrochloric Acid SCHEMBL5739434 | 0.66 | KDM4C (0.50) | KDM4EMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426113-A1 | CARBINOL COMPOUND HAVING HETEROCYCLIC LINKER | Kowa Company, Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |