Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6035089 | 0.79 | HRH3 (0.45) | HRH3L3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL9858541 | 0.76 | KDM4C (0.47) | L3MBTL1TDP1KDM4CALDH1A1KMT2A | |
| SCHEMBL6034963 | 0.75 | HRH3 (0.54) | HRH3L3MBTL1TDP1CYP1A2CYP3A4 | |
| SCHEMBL28079169 | 0.74 | KDM4C (0.46) | L3MBTL1TDP1KDM4CALDH1A1KMT2A | |
| SCHEMBL11284708 | 0.74 | FOLH1 (0.58) | L3MBTL1TDP1KDM4CALDH1A1KMT2A | |
| SCHEMBL258369 | 0.74 | KDM4C (0.51) | L3MBTL1TDP1CYP1A2CYP3A4KDM4C | |
| SCHEMBL169608 | 0.74 | KDM4E (0.38) | TDP1CYP3A4KDM4CALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL5739434 | 0.73 | KDM4C (0.50) | L3MBTL1TDP1CYP1A2CYP3A4KDM4C | |
| SCHEMBL123203 | 0.72 | KDM4C (0.51) | L3MBTL1TDP1KDM4CALDH1A1KMT2A | |
| SCHEMBL3880004 | 0.72 | KDM4C (0.50) | L3MBTL1TDP1KDM4CALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885697-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006121719-A2 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND METHODS OF USING SAME | BOEHRINGER INGELHEIM INTERNATIONAL, GMBH (DE) | 2006-11-16 | — | — | WO | disclosed |