SCHEMBL16961306

SCHEMBL16961306

C=Cc1cc(OCC)ccc1I

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.45
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
NPC1 O15118 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
TP53 P04637 2/20 0.38
CYP3A4 P08684 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 1/20 0.38
ESR2 Q92731 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.37
RELA Q04206 1/20 0.37
ESR1 P03372 2/20 0.37
AHR P35869 1/20 0.37
LTA4H P09960 1/20 0.36
CA12 O43570 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28014664 0.82 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL16956494 0.82 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL16959829 0.80 NQO1 (0.46) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL8173931 0.80 NQO1 (0.46) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL16310056 0.79 ERN1 (0.43) KMT2AMEN1NPC1TSHRTP53
SCHEMBL16956264 0.79 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL16951834 0.79 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL8905764 0.79 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL16310074 0.79 NQO1 (0.45) NQO1KMT2AMEN1NPC1APOBEC3G
SCHEMBL6673034 0.79 ALDH1A1 (0.45) NQO1KMT2AMEN1NPC1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2900645-A1 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION Bayer CropScience AG (DE) 2015-08-05 EP disclosed