Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 5/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959735 | 0.86 | KDM4E (0.37) | AHRPPARGKDM4ESMN1; SMN2ACACB | |
| SCHEMBL16952179 | 0.85 | AHR (0.39) | AHRPTGESALOX5PPARGKDM4E | |
| SCHEMBL16960271 | 0.84 | AHR (0.43) | AHRPTGESALOX5PPARGKDM4E | |
| SCHEMBL13261657 | 0.84 | PTGES (0.46) | AHRPTGESALOX5PPARGKDM4E | |
| SCHEMBL16953237 | 0.83 | CNR1 (0.42) | AHRPTGESALOX5PPARGTLR4 | |
| SCHEMBL16958515 | 0.83 | CNR1 (0.43) | AHRPTGESALOX5PPARGSMN1; SMN2 | |
| SCHEMBL16951633 | 0.83 | ACACB (0.33) | SMN1; SMN2ACACB | |
| SCHEMBL16961381 | 0.80 | PTGES (0.41) | PTGESALOX5PPARGKDM4ECYP1A2 | |
| SCHEMBL16952305 | 0.80 | CYP1A1 (0.39) | AHRALOX5KDM4ECYP1A2HDAC6 | |
| SCHEMBL16959787 | 0.79 | AHR (0.50) | AHRPTGESALOX5PPARGCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |