Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29581343 | 0.83 | MAPT (0.68) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL19122280 | 0.83 | MAPT (0.58) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL885028 | 0.83 | MAPT (0.68) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL16954389 | 0.83 | MAPT (0.51) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL16954494 | 0.83 | KDM4E (0.50) | MAPTHTTNPSR1MEN1KMT2A | |
| SCHEMBL16961942 | 0.83 | MAPT (0.45) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL8037824 | 0.83 | MAPT (0.69) | MAPTHTTCA12CA1CA2 | |
| SCHEMBL16960187 | 0.81 | MAPT (0.44) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL16952052 | 0.81 | MAPT (0.45) | MAPTHTTNPSR1CA12CA1 | |
| SCHEMBL12228747 | 0.81 | MAPT (0.82) | MAPTHTTNPSR1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |