SCHEMBL885028

SCHEMBL885028

COc1ccc(OC)c(C(C)=O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.68
HTT P42858 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
ALDH1A1 P00352 4/20 0.61
HPGD P15428 2/20 0.61
CYP3A4 P08684 1/20 0.61
MAPK1 P28482 1/20 0.61
KMT2A Q03164 3/20 0.60
POLB P06746 2/20 0.58
ABCG2 Q9UNQ0 1/20 0.58
CYP2C9 P11712 1/20 0.55
RXFP1 Q9HBX9 1/20 0.55
MEN1 O00255 1/20 0.54
PDE4A P27815 1/20 0.54
PDE4B Q07343 1/20 0.54
PDE4C Q08493 1/20 0.54
PDE4D Q08499 1/20 0.54
RAB9A P51151 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581343 1.00 MAPT (0.68) MAPTHTTNPSR1ALDH1A1HPGD
SCHEMBL27946281 0.87 MAPT (0.64) MAPTHTTNPSR1ALDH1A1HPGD
SCHEMBL12228747 0.86 MAPT (0.82) MAPTHTTNPSR1ALDH1A1HPGD
SCHEMBL13019654 0.85 MAPT (0.55) MAPTHTTNPSR1ALDH1A1HPGD
SCHEMBL28556103 0.85 MAPT (0.64) MAPTHTTNPSR1ALDH1A1HPGD
Peonol Methyl Ether SCHEMBL29402500 0.84 ALDH1A1 (0.67) MAPTHTTALDH1A1HPGDCYP3A4
Peonol Methyl Ether SCHEMBL4700333 0.84 ALDH1A1 (0.67) MAPTHTTALDH1A1HPGDCYP3A4
Peonol Methyl Ether SCHEMBL246262 0.84 ALDH1A1 (0.67) MAPTHTTALDH1A1HPGDCYP3A4
SCHEMBL563973 0.84 ALDH1A1 (0.56) MAPTHTTNPSR1ALDH1A1HPGD
SCHEMBL503802 0.84 POLB (0.70) MAPTHTTNPSR1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 346 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2925139-B1 FERMENTED SOIL ADDITIVE LIQUID FERTILISER SYSTEMS PTY LTD (AU) 2025-04-30 EP claimed
US-20240400784-A1 Method for Screening Solvent for Extracting Polyvinyl Chloride, Method for Recycling Waste, Recycled Polyvinyl Chloride, and Composition LG CHEM, LTD. (KR) 2024-12-05 US claimed
US-20240392094-A1 Method for Screening Solvent for Polyvinyl Chloride Extraction, Recycling Method for Waste Material, and Recycled Polyvinyl Chloride and Composition LG CHEM, LTD. (KR) 2024-11-28 US claimed
CN-117897440-A Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN claimed
WO-2023033605-A1 METHOD FOR SCREENING SOLVENT FOR EXTRACTING POLYVINYL CHLORIDE, METHOD FOR RECYCLING WASTE, RECYCLED POLYVINYL CHLORIDE, AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
WO-2023033601-A1 METHOD FOR SCREENING SOLVENT FOR POLYVINYL CHLORIDE EXTRACTION, RECYCLING METHOD FOR WASTE MATERIAL, AND RECYCLED POLYVINYL CHLORIDE AND COMPOSITION 주식회사 엘지화학 2023-03-09 WO claimed
CN-115745812-A Preparation method of 2-amino-1- (2,5-dimethoxyphenyl) ethanol 成都沣德煜晟医药科技有限公司 2023-03-07 CN claimed
CN-105755944-A Bridge construction method 张译元 2016-07-13 CN claimed
CN-104230755-A Chalcone derivative as well as preparation method and application thereof WUXI AIDE MEITE BIOLOG SCIENCE & TECHNOLOGY CO LTD 2014-12-24 CN claimed
US-8148537-B2 Substituted acetophenones useful as PDE4 inhibitors LEO PHARMA A/S (DK) 2012-04-03 US claimed
US-20110306775-A1 SYNTHESIS AND BIOLOGICAL EVALUATION OF 2',5'-DIMETHOXYCHALCONE DERIVATIVES AS MICROTUBULE-TARGETED ANTICANCER AGENTS KAOHSIUNG MEDICAL UNIVERSITY (TW) 2011-12-15 US claimed
EP-2125736-B1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS LEO PHARMA AS (DK) 2011-03-30 EP claimed
US-20100035908-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS LEO PHARMA (DK) 2010-02-11 US claimed
EP-2125736-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS Leo Pharma A/S (DK) 2009-12-02 EP claimed
WO-2008077404-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS LEO PHARMA A/S (DK) 2008-07-03 WO claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
EP-1455736-A1 RESTRUCTURING AND FINISHING OF KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2004-09-15 EP claimed
WO-2003053375-A1 RESTRUCTURING AND FINISHING OF KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-07-03 WO claimed
US-4456755-A ANTIBIOTICS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1984-06-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100035908-A1 SUBSTITUTED ACETOPHENONES USEFUL AS PDE4 INHIBITORS PDE4A, PDE4B, PDE3B MAPT 4649/4885HTT 3018/4885NPSR1 917/4885
US-20110306775-A1 SYNTHESIS AND BIOLOGICAL EVALUATION OF 2',5'-DIMETHOXYCHALCONE DERIVATIVES AS MICROTUBULE-TARGETED ANTICANCER AGENTS TUBB1, TUBB6, TUBA1C MAPT 109/4885HTT 997/4885NPSR1 4661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.