Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962661 | 1.00 | KDM4E (0.50) | KDM4EMAPTLMNAERN1CYP3A4 | |
| SCHEMBL16962641 | 0.79 | MAPT (0.58) | KDM4EMAPTLMNAERN1CYP3A4 | |
| SCHEMBL16962638 | 0.79 | MAPT (0.58) | KDM4EMAPTLMNAERN1CYP3A4 | |
| SCHEMBL15841249 | 0.75 | MAPT (0.53) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL3652492 | 0.75 | MAPT (0.53) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL3652495 | 0.75 | MAPT (0.53) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL2445195 | 0.75 | KDM4E (0.57) | KDM4EMAPTLMNACYP3A4MEN1 | |
| SCHEMBL2445194 | 0.75 | KDM4E (0.57) | KDM4EMAPTLMNACYP3A4MEN1 | |
| SCHEMBL18980187 | 0.73 | KMT2A (0.50) | KDM4EMAPTLMNAMEN1KMT2A | |
| SCHEMBL1036682 | 0.73 | KDM4E (0.44) | KDM4EMAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900661-A2 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | claimed |