Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16962638 | 1.00 | MAPT (0.58) | MAPTHTTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL16962661 | 0.79 | KDM4E (0.50) | MAPTHTTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL16962659 | 0.79 | KDM4E (0.50) | MAPTHTTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL2456594 | 0.77 | KMT2A (0.63) | MAPTHTTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL15841249 | 0.75 | MAPT (0.53) | MAPTHTTHSP90AA1LMNAMEN1 | |
| SCHEMBL3652492 | 0.75 | MAPT (0.53) | MAPTHTTHSP90AA1LMNAMEN1 | |
| SCHEMBL3652495 | 0.75 | MAPT (0.53) | MAPTHTTHSP90AA1LMNAMEN1 | |
| SCHEMBL509268 | 0.74 | AMY1A (0.57) | MAPTHTTLMNAMEN1KMT2A | |
| SCHEMBL7846678 | 0.74 | HSP90AA1 (0.66) | MAPTHTTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL509267 | 0.74 | AMY1A (0.57) | MAPTHTTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776993-B2 | Nitrogen-containing heterocyclic compounds for plant disease control | BAYER CROPSCIENCE AG (DE) | 2017-10-03 | — | — | US | claimed |
| US-20170057951-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | claimed |
| US-20150216172-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | claimed |
| US-9776993-B2 | Nitrogen-containing heterocyclic compounds for plant disease control | BAYER CROPSCIENCE AG (DE) | 2017-10-03 | — | — | US | disclosed |
| US-20170057951-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | BAYER CROPSCIENCE AG | 2017-03-02 | — | — | US | disclosed |
| US-9510598-B2 | Nitrogen-containing heterocyclic compounds for plant disease control | BAYER CROPSCIENCE AG (DE) | 2016-12-06 | — | — | US | disclosed |
| EP-2900661-B1 | QUINOLINE ISOXAZOLIN DERIVATIVES FOR PLANT DISEASE CONTROL | BAYER CROPSCIENCE AG (DE) | 2016-10-26 | — | — | EP | disclosed |
| US-20150216172-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
| EP-2900661-A2 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150216172-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | NOD1, BROX, CBR3 | MAPT 1198/4885HTT 919/4885HSP90AA1 2952/4885 |
| US-20170057951-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS FOR PLANT DISEASE CONTROL | NOD1, BROX, CBR3 | MAPT 1198/4885HTT 919/4885HSP90AA1 2952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.