Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1320015 | 0.81 | KDM4E (0.52) | SMN1; SMN2KDM4ENPC1LMNARAB9A | |
| SCHEMBL29675219 | 0.78 | GAA (0.85) | MAPTMEN1KMT2AGAAGFER | |
| SCHEMBL501924 | 0.78 | GAA (0.85) | MAPTMEN1KMT2AGAAGFER | |
| SCHEMBL10055001 | 0.78 | GAA (0.85) | MAPTMEN1KMT2AGAAGFER | |
| SCHEMBL13533520 | 0.77 | MAPT (0.72) | MAPTMEN1KMT2AGAAGFER | |
| SCHEMBL1320017 | 0.77 | MEN1 (0.48) | MAPTMEN1KMT2AGAAGFER | |
| Hydrochloric Acid SCHEMBL1804763 | 0.76 | GAA (0.82) | MAPTMEN1KMT2AGAAGFER | |
| SCHEMBL15673192 | 0.76 | KMT2A (0.40) | MEN1KMT2AGAAHPGDSMN1; SMN2 | |
| SCHEMBL15673191 | 0.76 | KMT2A (0.40) | MEN1KMT2AGAAHPGDSMN1; SMN2 | |
| SCHEMBL15673254 | 0.76 | SMN1; SMN2 (0.46) | MAPTMEN1KMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362775-B1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2015-08-05 | — | — | EP | disclosed |