Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10038567 | 0.88 | MDM2 (0.39) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL15602040 | 0.83 | — | — | |
| SCHEMBL15573001 | 0.82 | MAPT (0.40) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL14839449 | 0.80 | MDM2 (0.54) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL15574080 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL15602009 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL10038574 | 0.71 | MDM2 (0.39) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL15602025 | 0.71 | MAPK14 (0.39) | ALDH1A1MAPTATMMDM2MAPK9 | |
| SCHEMBL14839452 | 0.70 | MDM2 (0.56) | ALDH1A1MAPTMDM2MAPK9MAPK10 | |
| SCHEMBL10038573 | 0.70 | MDM2 (0.43) | ALDH1A1MAPTATMMDM2MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | SOLVAY (BE) | 2015-08-06 | — | — | US | disclosed |
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | SOLVAY (BE) | 2015-08-06 | — | — | US | disclosed |
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | SOLVAY (BE) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | AP2M1, AP3M1, AP1M1 | ALDH1A1 3958/4885MAPT 95/4885ATM 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.