Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12503324 | 0.97 | PPARA (0.60) | PPARAPPARGSIRT2PTGIRPLA2G4B | |
| SCHEMBL370943 | 0.94 | PPARA (0.49) | PPARAPPARGSIRT2MAPK1CTSV | |
| SCHEMBL367806 | 0.87 | PLA2G4B (0.57) | PPARAPPARGSIRT2PLA2G4BMTNR1A | |
| SCHEMBL343814 | 0.84 | PPARA (0.54) | PPARAPPARGPTGIRMAPK1TRPV1 | |
| SCHEMBL368053 | 0.82 | PPARA (0.44) | PPARAPPARGPTGIRPLA2G4BMAPK1 | |
| SCHEMBL1697117 | 0.81 | SIRT2 (0.41) | PPARAPPARGSIRT2CTSVCTSL | |
| SCHEMBL345673 | 0.81 | PPARA (0.58) | PPARAPPARGPTGIRMAPK1MDH1 | |
| SCHEMBL344565 | 0.81 | PPARA (0.60) | PPARAPPARGPTGIRPLA2G4BMAPK1 | |
| SCHEMBL345013 | 0.81 | PPARA (0.60) | PPARAPPARGPTGIRPLA2G4BMAPK1 | |
| SCHEMBL12503223 | 0.80 | MAPK1 (0.42) | PPARAPPARGSIRT2MAPK1CTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012003145-A2 | THERAPEUTIC AGENTS FOR OCULAR HYPERTENSION | ALLERGAN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |