Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 10/20 | 0.42 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984192 | 0.82 | KCNH2 (0.40) | KCNH2LOXL2 | |
| SCHEMBL16984189 | 0.81 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL16972674 | 0.81 | KCNH2 (0.47) | KCNH2NEK1 | |
| SCHEMBL16984186 | 0.77 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL16972729 | 0.74 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL16972688 | 0.74 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL16972727 | 0.71 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL16984188 | 0.68 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL17597567 | 0.66 | DAO (0.35) | LOXL2 | |
| Hydrochloric Acid SCHEMBL17597574 | 0.65 | DAO (0.34) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015114317-A1 | 5H-ISOTHIAZOLO[4,5-C]PYRIDINE-3,4-DIONE OR 5H-PYRAZOLO[4,3-C]PYRIDIN-3,4-DIONE AS ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2015-08-06 | — | — | WO | disclosed |