Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.43 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methoxycinnamic Acid SCHEMBL1548518 | 0.97 | TDP1 (0.60) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL126604 | 0.89 | TDP1 (0.56) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL17627791 | 0.89 | TDP1 (0.56) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL5198950 | 0.89 | TDP1 (0.56) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL1959631 | 0.87 | TDP1 (0.47) | TDP1THRBTAS1R3TAS1R1ALDH1A1 | |
| Octinoxate SCHEMBL30081040 | 0.86 | TDP1 (0.79) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL527532 | 0.85 | TDP1 (0.64) | TDP1THRBATMTAS1R3TAS1R1 | |
| SCHEMBL3878976 | 0.84 | CYP3A4 (0.46) | TDP1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL5677176 | 0.83 | TDP1 (0.50) | TDP1THRBTAS1R3TAS1R1MAPT | |
| Cinoxate SCHEMBL12099393 | 0.83 | TDP1 (0.62) | TDP1THRBATMTAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3099301-A2 | TREATMENTS FOR RESISTANT ACNE | Vyome Biosciences Pvt Ltd (IN) | 2016-12-07 | — | — | EP | disclosed |
| WO-2015114666-A2 | TREATMENTS FOR RESISTANT ACNE | VYOME BIOSCIENCES PVT. LTD. (IN) | 2015-08-06 | — | — | WO | disclosed |