SCHEMBL5677176

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17627791	0.93	TDP1 (0.56)	TDP1ALOX5TAS1R3TAS1R1MMP1
	SCHEMBL5198950	0.93	TDP1 (0.56)	TDP1ALOX5TAS1R3TAS1R1MMP1
	SCHEMBL126604	0.93	TDP1 (0.56)	TDP1ALOX5TAS1R3TAS1R1MMP1
	SCHEMBL39941	0.87	APEX1 (0.53)	TDP1ALOX5APEX1CNR1PPARG
	SCHEMBL2489081	0.87	APEX1 (0.53)	TDP1ALOX5APEX1CNR1PPARG
	SCHEMBL9301856	0.87	APEX1 (0.53)	TDP1ALOX5APEX1CNR1PPARG
	4-Methoxycinnamic Acid SCHEMBL1548518	0.86	TDP1 (0.60)	TDP1TAS1R3TAS1R1THRB
	SCHEMBL2490383	0.86	ALOX5 (0.54)	TDP1ALOX5APEX1CNR1PPARG
	SCHEMBL7181298	0.86	TDP1 (0.42)	TDP1ALOX5TAS1R3TAS1R1CNR1
	Octinoxate SCHEMBL29435124	0.84	TDP1 (0.76)	TDP1ALOX5TAS1R3TAS1R1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.