SCHEMBL16972759

SCHEMBL16972759

Cc1cnccn1.Cc1cnccn1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
KDM4E B2RXH2 4/20 0.39
NAPRT Q6XQN6 1/20 0.39
HCAR2 Q8TDS4 1/20 0.39
UHRF1 Q96T88 1/20 0.38
CYP1A2 P05177 1/20 0.38
BAZ2B Q9UIF8 1/20 0.37
ADORA3 P0DMS8 1/20 0.37
TSHR P16473 1/20 0.37
MC4R P32245 1/20 0.37
ADRA1A P35348 1/20 0.37
MC3R P41968 1/20 0.37
ALDH1A1 P00352 2/20 0.36
GRM5 P41594 1/20 0.36
HPGD P15428 1/20 0.36
POLB P06746 1/20 0.35
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29363842 1.00
SCHEMBL12345 1.00
Water SCHEMBL28543836 0.97
SCHEMBL30909437 0.97
SCHEMBL28281264 0.97
Pyrazine SCHEMBL61481 0.97 HSP90AA1 (0.43) HSP90AA1KDM4ENAPRTHCAR2UHRF1
Ammonia Solution, Strong SCHEMBL2856209 0.97
Ethane SCHEMBL162068 0.97
Pyrazine SCHEMBL1521406 0.97 HSP90AA1 (0.43) HSP90AA1KDM4ENAPRTHCAR2UHRF1
Pyrazine SCHEMBL1521570 0.97 HSP90AA1 (0.43) HSP90AA1KDM4ENAPRTHCAR2UHRF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015116801-A2 COMPOSITIONS AND METHODS FOR CAPTURING, KILLING OR REPELLING BED BUGS OLFACTOR LABORATORIES, INC. (US) 2015-08-06 WO disclosed