Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.64 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.64 |
| ▸ | HTR6 | P50406 | 19/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL798695 | 0.92 | CHRM2 (0.67) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL774519 | 0.92 | CHRM2 (0.67) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL1067208 | 0.84 | CHRM2 (0.64) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL1067210 | 0.84 | CHRM2 (0.64) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL29387278 | 0.81 | CHRM2 (0.57) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL19171029 | 0.78 | HTR1B (0.80) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Eletriptan SCHEMBL798473 | 0.78 | HTR1B (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Eletriptan SCHEMBL29414096 | 0.78 | HTR1B (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Eletriptan SCHEMBL1556539 | 0.78 | HTR1B (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Eletriptan SCHEMBL26719 | 0.78 | HTR1B (1.00) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004811-A1 | PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE | IND-SWIFT LABORATORIES LIMITED (IN) | 2012-01-12 | — | — | WO | disclosed |