Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL1697449

CCCCCCCCCCCCCCCCC(Br)(CCCCCCCCCCCCCCCC)CCCCCCCCCCCCCCCC.N

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
THRB P10828 1/20 0.47
SLC22A1 O15245 2/20 0.43
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
GGPS1 O95749 6/20 0.41
FDPS P14324 8/20 0.39
SLC22A2 O15244 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL11212815 1.00 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1TP53
Ammonia Solution, Strong SCHEMBL2210353 1.00 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1TP53
Ammonia Solution, Strong SCHEMBL2315629 1.00 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1TP53
SCHEMBL27704949 0.97 TSHR (0.50) TSHRTHRBSLC22A1ALDH1A1TP53
Ammonia Solution, Strong SCHEMBL11364094 0.94 TSHR (0.39) TSHRTHRBSLC22A1ALDH1A1TP53
Phosphine SCHEMBL1535966 0.94 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1TP53
Phosphine SCHEMBL10694267 0.94 TSHR (0.47) TSHRTHRBSLC22A1ALDH1A1TP53
SCHEMBL8601485 0.94 TSHR (0.44) TSHRTHRBSLC22A1ALDH1A1TP53
SCHEMBL10430444 0.92 TSHR (0.44) TSHRTHRBSLC22A1ALDH1A1TP53
SCHEMBL29218396 0.91 TSHR (0.41) TSHRTHRBSLC22A1ALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107051447-A The preparation method of ozone Heterogeneous oxidation solid catalyst 四川师范大学 2017-08-18 CN disclosed
CN-107020119-A The preparation method of ozone Heterogeneous oxidation solid catalyst 四川师范大学 2017-08-08 CN disclosed
CN-107008476-A The preparation method of ozone Heterogeneous oxidation solid catalyst 四川师范大学 2017-08-04 CN disclosed
CN-107008475-A The preparation method of ozone Heterogeneous oxidation solid catalyst 四川师范大学 2017-08-04 CN disclosed
WO-2012004811-A1 PROCESS FOR THE PREPARATION OF 5-SUBSTSITUTED INDOLE DERIVATIVE IND-SWIFT LABORATORIES LIMITED (IN) 2012-01-12 WO disclosed
EP-0971997-B1 HARD-SURFACE CLEANING COMPOSITIONS UNILEVER PLC (GB) 2003-07-23 EP disclosed
EP-0971997-A1 HARD-SURFACE CLEANING COMPOSITIONS UNILEVER PLC (GB) 2000-01-19 EP disclosed
WO-1998040452-A1 HARD-SURFACE CLEANING COMPOSITIONS UNILEVER PLC (GB) 1998-09-17 WO disclosed