Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.56 |
| ▸ | PTGIR | P43119 | 9/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1838402 | 0.96 | PTGIR (0.56) | PTGDR2PTGIRACHETBXAS1 | |
| SCHEMBL1838407 | 0.96 | PTGIR (0.56) | PTGDR2PTGIRACHETBXAS1 | |
| SCHEMBL10465049 | 0.85 | ACHE (0.48) | PTGDR2PTGIRACHETBXAS1 | |
| SCHEMBL14120749 | 0.83 | ACHE (0.45) | PTGDR2PTGIRACHE | |
| SCHEMBL16977037 | 0.81 | PTGDR2 (0.55) | PTGDR2PTGIRACHETBXAS1PTGDR | |
| SCHEMBL8858726 | 0.80 | PTGIR (0.56) | PTGDR2PTGIRTBXAS1 | |
| SCHEMBL1841769 | 0.79 | ACHE (0.46) | PTGDR2PTGIRACHE | |
| SCHEMBL1845899 | 0.79 | ACHE (0.46) | PTGDR2PTGIRACHE | |
| SCHEMBL9050868 | 0.79 | PTGIR (0.64) | PTGDR2PTGIRTBXAS1 | |
| Hydrochloric Acid SCHEMBL1845895 | 0.78 | ACHE (0.47) | PTGDR2PTGIRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718264-B1 | BENZOCYCLOHEPTENE ACETIC ACIDS | HOFFMANN LA ROCHE (CH) | 2015-08-05 | — | — | EP | disclosed |