Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16930463 | 1.00 | MME (0.56) | MMEACE | |
| SCHEMBL16939323 | 0.86 | MME (0.53) | MME | |
| SCHEMBL16979113 | 0.86 | MME (0.63) | MMEACE | |
| SCHEMBL16939260 | 0.86 | MME (0.63) | MMEACE | |
| SCHEMBL18010010 | 0.85 | MME (0.55) | MMEACE | |
| SCHEMBL18040125 | 0.85 | MME (0.55) | MMEACE | |
| SCHEMBL18724753 | 0.85 | MME (0.55) | MMEACE | |
| SCHEMBL16939240 | 0.85 | MME (0.55) | MMEACE | |
| SCHEMBL17980192 | 0.85 | MME (0.55) | MMEACE | |
| SCHEMBL12317524 | 0.85 | MME (0.55) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015116786-A1 | NEPRILYSIN INHIBITORS | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2015-08-06 | — | — | WO | disclosed |