Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 20/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16939240 | 1.00 | MME (0.55) | MMEACE | |
| SCHEMBL17980192 | 1.00 | MME (0.55) | MMEACE | |
| SCHEMBL18724753 | 1.00 | MME (0.55) | MMEACE | |
| SCHEMBL16939260 | 0.90 | MME (0.63) | MMEACE | |
| SCHEMBL16979113 | 0.90 | MME (0.63) | MMEACE | |
| SCHEMBL18597832 | 0.90 | MMEL1 (0.46) | MMEACE | |
| SCHEMBL14919312 | 0.90 | MMEL1 (0.46) | MMEACE | |
| SCHEMBL14891060 | 0.90 | MMEL1 (0.46) | MMEACE | |
| SCHEMBL18010010 | 0.89 | MME (0.55) | MMEACE | |
| SCHEMBL12317524 | 0.89 | MME (0.55) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9433598-B2 | (2S,4R)-5-(5′-chloro-2′-fluorobiphenyl-4-yl)-4-(ethoxyoxalylamino)-2-hydroxymethyl-2-methylpentanoic acid | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2016-09-06 | — | — | US | disclosed |