SCHEMBL1698199

SCHEMBL1698199

CCC(C)C1CCc2cccnc21.CCCC(C)C1CCc2cccnc21

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 9/20 0.36
KCNH2 Q12809 9/20 0.36
DRD2 P14416 1/20 0.36
DRD3 P35462 1/20 0.36
CXCR4 P61073 7/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698219 0.96 DRD2 (0.38) OPRL1KCNH2DRD2DRD3CXCR4
SCHEMBL1698223 0.93 OPRL1 (0.40) OPRL1KCNH2DRD2DRD3CXCR4
SCHEMBL1698226 0.92 CXCR4 (0.41) KCNH2CXCR4
SCHEMBL1701122 0.88 CXCR4 (0.38) KCNH2CXCR4
SCHEMBL1698196 0.88 CXCR4 (0.43) KCNH2CXCR4
SCHEMBL1698222 0.85 CXCR4 (0.44) KCNH2CXCR4
SCHEMBL19435835 0.83 CXCR4 (0.40) OPRL1KCNH2CXCR4
SCHEMBL1698203 0.83 OPRL1 (0.34) OPRL1KCNH2
SCHEMBL1698228 0.80 OPRL1 (0.40) OPRL1KCNH2DRD2DRD3CXCR4
SCHEMBL25515629 0.78 OPRL1 (0.40) OPRL1KCNH2DRD2CXCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2584916-A1 ORGANIC COMPOUNDS Givaudan SA (CH) 2013-05-01 EP claimed
WO-2011160254-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2011-12-29 WO claimed
WO-2011161163-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2011-12-29 WO claimed