Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FHIT | P49789 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1750835 | 0.82 | KMT2A (0.77) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL4483384 | 0.79 | POLB (0.63) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL9184563 | 0.79 | POLB (1.00) | POLBKMT2AMAPK1 | |
| SCHEMBL11519772 | 0.77 | KMT2A (0.55) | ALDH1A1POLBKMT2AGAAMEN1 | |
| SCHEMBL11274830 | 0.76 | KMT2A (0.55) | ALDH1A1POLBKMT2AGAAMEN1 | |
| SCHEMBL16569044 | 0.76 | POLB (0.54) | ALDH1A1POLBKMT2AMEN1MAPT | |
| SCHEMBL518434 | 0.76 | KMT2A (0.61) | ALDH1A1POLBKMT2AGAAMEN1 | |
| SCHEMBL28734569 | 0.75 | ALDH1A1 (0.74) | ALDH1A1KDM4EKMT2AGAAMEN1 | |
| SCHEMBL519301 | 0.75 | CYP1A2 (0.63) | ALDH1A1POLBKMT2AGAAMEN1 | |
| SCHEMBL518604 | 0.74 | KMT2A (0.67) | ALDH1A1POLBKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160189-A1 | METHOD OF SCREENING FOR INHIBITORS OF sPLA2-IIA | SCOTT KIERAN (AU) | 2011-12-29 | — | — | WO | disclosed |
| WO-2011160189-A1 | METHOD OF SCREENING FOR INHIBITORS OF sPLA2-IIA | SCOTT KIERAN (AU) | 2011-12-29 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |