Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KCNQ4 | P56696 | 3/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28524651 | 0.91 | AAK1 (0.35) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL18427958 | 0.91 | IDO1 (0.37) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL28290422 | 0.91 | IDO1 (0.37) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL16970590 | 0.91 | AAK1 (0.35) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL16974965 | 0.91 | IDO1 (0.37) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL28524652 | 0.91 | AAK1 (0.35) | AAK1LMNASMN1; SMN2ATMKCNQ4 | |
| SCHEMBL18428120 | 0.85 | LMNA (0.36) | AAK1LMNASMN1; SMN2ATMHTT | |
| SCHEMBL28907018 | 0.85 | LMNA (0.36) | AAK1LMNASMN1; SMN2ATMHTT | |
| SCHEMBL16970592 | 0.84 | LMNA (0.36) | LMNASMN1; SMN2KCNQ4KCNQ5KMT2A | |
| SCHEMBL16974981 | 0.83 | IDO1 (0.40) | AAK1LMNASMN1; SMN2ATMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015117147-A1 | BETA-SUBSTITUTED BETA-AMINO ACIDS AND ANALOGS AS CHEMOTHERAPEUTIC AGENTS | QUADRIGA BIOSCIENCES, INC. (US) | 2015-08-06 | — | — | WO | disclosed |