Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19565413 | 0.80 | KDM1A (0.47) | MEN1ALDH1A1LMNAKMT2AHTR2A | |
| SCHEMBL29388679 | 0.73 | TSHR (0.44) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL149965 | 0.73 | TSHR (0.44) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL28527151 | 0.72 | HTR2A (0.35) | HTR2ADRD1 | |
| SCHEMBL29901667 | 0.70 | HTR2A (0.61) | HTR2ADRD2DRD1 | |
| SCHEMBL9927291 | 0.70 | HTR2A (0.34) | HTR2ADRD1 | |
| SCHEMBL8816862 | 0.70 | HTR2A (0.61) | HTR2ADRD2DRD1 | |
| SCHEMBL28413388 | 0.68 | PDK2 (0.40) | ALDH1A1HTR2ADRD1 | |
| SCHEMBL29828278 | 0.68 | PDK2 (0.40) | ALDH1A1HTR2ADRD1 | |
| SCHEMBL30843843 | 0.68 | HTR2A (0.59) | HTR2ADRD2KDM1ADRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011160764-A1 | POLYMERIZABLE COMPOUNDS AND USE THEREOF IN LIQUID CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |