SCHEMBL149965

SCHEMBL149965

c1cc2c3c(c1)CCc1cccc(c1-3)CC2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
CES1 P23141 1/20 0.41
MEN1 O00255 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
KDM4E B2RXH2 2/20 0.40
HPGD P15428 2/20 0.40
GAA P10253 1/20 0.40
ORAI1 Q96D31 1/20 0.39
ORAI2 Q96SN7 1/20 0.39
ORAI3 Q9BRQ5 1/20 0.39
CYP2A6 P11509 1/20 0.39
HTR2C P28335 1/20 0.38
CYP3A4 P08684 2/20 0.36
SRD5A1 P18405 1/20 0.36
BCL2L1 Q07817 1/20 0.36
BAD Q92934 1/20 0.36
HSD17B10 Q99714 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29388679 1.00 TSHR (0.44) TSHRCES1MEN1ALDH1A1MAPT
SCHEMBL982854 0.90 TSHR (0.46) TSHRCES1MEN1ALDH1A1MAPT
SCHEMBL5571743 0.81 MAPT (0.40) TSHRMEN1ALDH1A1MAPTKMT2A
SCHEMBL4411314 0.81 TDP1 (0.38) TSHRCES1MEN1ALDH1A1MAPT
SCHEMBL12023190 0.78 ALDH1A1 (0.54) TSHRMEN1ALDH1A1MAPTKMT2A
SCHEMBL5399227 0.77 TSHR (0.52) TSHRMEN1ALDH1A1MAPTKMT2A
SCHEMBL13926200 0.77 KMT2A (0.36) MEN1ALDH1A1MAPTKMT2ALMNA
SCHEMBL29351986 0.75
SCHEMBL33555 0.75
SCHEMBL34906 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999819-B2 Formulation containing a highly branched polymer, highly branched polymer and electro-optical device containing this highly branched polymer MERCK PATENT GMBH (DE) 2024-06-04 US claimed
US-20210277176-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2021-09-09 US claimed
EP-3821477-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER Merck Patent GmbH (DE) 2021-05-19 EP claimed
CN-112352331-A Formulations containing highly branched polymers, highly branched polymers and electro-optical devices containing such highly branched polymers 默克专利有限公司 2021-02-09 CN claimed
WO-2020011701-A1 FORMULATION CONTAINING A HIGHLY BRANCHED POLYMER, HIGHLY BRANCHED POLYMER AND ELECTRO-OPTICAL DEVICE CONTAINING THIS HIGHLY BRANCHED POLYMER MERCK PATENT GMBH (DE) 2020-01-16 WO claimed
US-10125214-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-11-13 US claimed
US-9793484-B2 Composition comprising polymeric organic semiconducting compounds MERCK PATENT GMBH (DE) 2017-10-17 US claimed
US-9728724-B2 Polymer containing aldehyde groups, reaction and crosslinking of this polymer, crosslinked polymer, and electroluminescent device comprising this polymer MERCK PATENT GMBH (DE) 2017-08-08 US claimed
US-9695274-B2 Polymers containing 2,7-pyrene structural units MERCK PATENT GMBH (DE) 2017-07-04 US claimed
EP-2401316-B1 POLYMER HAVING ALDEHYDE GROUPS, CONVERTING AND CROSS-LINKING OF SAID POLYMER, CROSS-LINKED POLYMER, AND ELECTROLUMINESCENT DEVICE COMPRISING SAID POLYMER MERCK PATENT GMBH (DE) 2017-05-24 EP claimed
EP-1741149-B1 ELECTROLUMINESCENT POLYMERS AND USE THEROF MERCK PATENT GMBH (DE) 2008-12-24 EP claimed
US-20080026135-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US claimed
US-20070281182-A1 Electroluminescent Polymers MERCK PATENT GMBH (DE) 2007-12-06 US claimed
US-7271406-B2 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY (US) 2007-09-18 US claimed
US-20070205714-A1 Electroluminescent Polymers and the Use Thereof MERCK PATENT GMBH (DE) 2007-09-06 US claimed
US-20060199943-A1 White-emitting copolymers, representation and use thereof OVION ORGANIC SEMICONDUCTORS GMBH (DE) 2006-09-07 US claimed
EP-1656408-A2 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF Covion Organic Semiconductors GmbH (DE) 2006-05-17 EP claimed
WO-2005014689-A2 CONJUGATED POLYMERS CONTAINING DIHYDROPHENANTHRENE UNITS AND USE THEREOF COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2005-02-17 WO claimed
EP-0699699-B1 Poly(4,5,9,10-tetrahydropyrene-2,7-diyl)-derivatives and their use as electroluminiscent materials AVENTIS RES & TECH GMBH & CO (DE) 1999-11-03 EP claimed
US-4476009-A Process for improving the hydrogen donor properties of a coal liquefaction solvent TEXACO INC. (US) 1984-10-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10125214-B2 Materials for electronic devices PEF1, PARG, EFNA1 TSHR 4427/4885CES1 3559/4885MEN1 1451/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.