Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | ACR | P10323 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19414437 | 0.92 | ESR1 (0.41) | TDP1HRH3ADORA3MAPTL3MBTL1 | |
| SCHEMBL19414621 | 0.92 | NPC1 (0.34) | TDP1HRH3ADORA3MAPTL3MBTL1 | |
| SCHEMBL16984005 | 0.88 | CNR2 (0.31) | TDP1MAPTL3MBTL1ESR1ESR2 | |
| SCHEMBL16983800 | 0.86 | ESR1 (0.39) | TDP1ADORA3MAPTL3MBTL1ESR1 | |
| SCHEMBL16983808 | 0.84 | ESR1 (0.38) | TDP1MAPTL3MBTL1ESR1ESR2 | |
| SCHEMBL16983807 | 0.84 | NPC1 (0.39) | TDP1HRH3ADORA3MAPTL3MBTL1 | |
| SCHEMBL19414761 | 0.82 | TDP1 (0.46) | TDP1HRH3MAPTL3MBTL1ESR1 | |
| SCHEMBL16983805 | 0.80 | ESR1 (0.37) | TDP1MAPTL3MBTL1ESR1ESR2 | |
| SCHEMBL19414622 | 0.79 | — | — | |
| SCHEMBL19414632 | 0.79 | ADORA3 (0.48) | TDP1HRH3ADORA3MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9778581-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20150220007-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2015-08-06 | — | — | US | disclosed |