Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | CTSV | O60911 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16984561 | 0.85 | MERTK (0.43) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16984557 | 0.85 | MERTK (0.44) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16984623 | 0.84 | MERTK (0.43) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16969526 | 0.84 | MERTK (0.45) | MERTKCYP2C9CYP2C19MAPTAKR1C3 | |
| SCHEMBL16984625 | 0.83 | MERTK (0.43) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2898995 | 0.78 | MERTK (0.59) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2902504 | 0.77 | MERTK (0.56) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL2896050 | 0.77 | MERTK (0.58) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16984626 | 0.77 | MERTK (0.43) | MERTKKCNH2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL16969353 | 0.76 | MERTK (0.44) | MERTKCYP2C9CYP2C19MAPTAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340492-B2 | Meta-Diarylaniline or meta-diarylpyridinamine compound, preparation method and medical uses thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2016-05-17 | — | — | US | disclosed |
| US-20150218088-A1 | META-DIARYLANILINE OR META-DIARYLPYRIDINAMINE COMPOUND, PREPARATION METHOD AND MEDICAL USES THEREOF | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218088-A1 | META-DIARYLANILINE OR META-DIARYLPYRIDINAMINE COMPOUND, PREPARATION METHOD AND MEDICAL USES THEREOF | QDPR, COMT, CYP2D6 | MERTK 3962/4885KCNH2 1217/4885CYP2C9 15/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.