Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 8/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 8/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 8/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16986162 | 0.97 | MAPT (0.52) | MAPTPOLBRECQLALDH1A1KDM4E | |
| SCHEMBL16986122 | 0.87 | MPO (0.47) | MAPTPOLBRECQLALDH1A1KDM4E | |
| SCHEMBL16986138 | 0.86 | KDM4E (0.51) | MAPTPOLBRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16986190 | 0.85 | KDM4E (0.50) | MAPTPOLBRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16986215 | 0.85 | MPO (0.45) | MAPTPOLBRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16986208 | 0.85 | MPO (0.45) | MAPTPOLBRECQLALDH1A1KDM4E | |
| SCHEMBL16986206 | 0.85 | KDM4E (0.43) | MAPTPOLBRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16986257 | 0.84 | KDM4E (0.42) | MAPTPOLBRECQLALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL16986204 | 0.84 | KDM4E (0.50) | MAPTALDH1A1KDM4EMAPK11MAPK14 | |
| SCHEMBL16986210 | 0.82 | HRH3 (0.48) | MAPTPOLBRECQLALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150266864-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) | 2015-09-24 | — | — | US | claimed |
| EP-2905278-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | Cristália Produtos Químicos Farmacêuticos LTDA. (BR) | 2015-08-12 | — | — | EP | claimed |
| US-20150266864-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | CRISTÁLIA PRODUTOS QUÍMICOS FARMACÊUTICOS LTDA (BR) | 2015-09-24 | — | — | US | disclosed |
| EP-2905278-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | Cristália Produtos Químicos Farmacêuticos LTDA. (BR) | 2015-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266864-A1 | HETEROAROMATIC COMPOUNDS, METHOD FOR PREPARING THE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, USES AND METHOD FOR TREATING ACUTE AND CHRONIC PAIN | TRPV1, AP1G1, INA | MAPT 4001/4885POLB 3969/4885RECQL 2229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.