Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 20/20 | 0.71 |
| ▸ | HTR2A | P28223 | 20/20 | 0.71 |
| ▸ | DRD3 | P35462 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1698913 | 0.90 | DRD2 (0.70) | DRD2HTR2ADRD3 | |
| SCHEMBL14874310 | 0.89 | DRD2 (0.71) | DRD2HTR2ADRD3 | |
| SCHEMBL12074824 | 0.89 | DRD2 (0.71) | DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL1698410 | 0.88 | DRD2 (0.70) | DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL1698456 | 0.88 | DRD2 (0.70) | DRD2HTR2ADRD3 | |
| Cyclopropane SCHEMBL15911217 | 0.85 | DRD2 (0.81) | DRD2HTR2ADRD3 | |
| SCHEMBL15911251 | 0.85 | DRD2 (0.81) | DRD2HTR2ADRD3 | |
| SCHEMBL14874309 | 0.84 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL15911353 | 0.84 | DRD2 (0.76) | DRD2HTR2ADRD3 | |
| SCHEMBL1698509 | 0.83 | DRD2 (1.00) | DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582705-A1 | ANELLATED PYRIDINE COMPOUNDS AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F.HOFFMANN-LA ROCHE AG (CH) | 2013-04-24 | — | — | EP | claimed |
| WO-2011161009-A1 | ANELLATED PYRIDINE COMPOUNDS AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2011-12-29 | — | — | WO | claimed |