⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4489372 | 0.73 | — | — | |
| SCHEMBL4570687 | 0.73 | — | — | |
| SCHEMBL28967675 | 0.71 | MAPT (0.34) | — | |
| SCHEMBL9496465 | 0.69 | — | — | |
| SCHEMBL12542106 | 0.68 | DAO (0.46) | — | |
| SCHEMBL12215731 | 0.68 | TSHR (0.42) | — | |
| SCHEMBL14227642 | 0.68 | MAPK1 (0.40) | — | |
| SCHEMBL10636900 | 0.67 | MAPT (0.39) | — | |
| SCHEMBL6354512 | 0.67 | PLAU (0.40) | — | |
| SCHEMBL3525406 | 0.67 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
| US-8349873-B2 | Factor XA inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-20120088795-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2012-04-12 | — | — | US | disclosed |
| CN-101784520-A | Novel malonic acid sulfonamide derivative and pharmaceutical use thereof | MITSUBISHI TANABE PHARMA CORP | 2010-07-21 | — | — | CN | disclosed |
| CN-100415750-C | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2008-09-03 | — | — | CN | disclosed |
| CN-1772749-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2006-05-17 | — | — | CN | disclosed |
| CN-1239495-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2006-02-01 | — | — | CN | disclosed |
| CN-1636457-A | Fungicides for the control of take-all disease of plants | MONSANTO CO (US) | 2005-07-13 | — | — | CN | disclosed |
| CN-1188419-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1188420-C | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 2005-02-09 | — | — | CN | disclosed |
| CN-1227099-A | Novel treatment agent | SMITHKLINE BEECHAM PLC (GB) | 1999-09-01 | — | — | CN | disclosed |
| CN-1225364-A | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 1999-08-11 | — | — | CN | disclosed |
| CN-1225365-A | Fungicides for control of take-all disease of plants | MONSANTO CO (US) | 1999-08-11 | — | — | CN | disclosed |
| CN-1221745-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-07-07 | — | — | CN | disclosed |
| CN-1221746-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-07-07 | — | — | CN | disclosed |
| CN-1043835-C | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1999-06-30 | — | — | CN | disclosed |
| CN-1094613-A | Novel therapeutic agents | SMITHKLINE BEECHAM PLC (GB) | 1994-11-09 | — | — | CN | disclosed |
| CN-1085221-A | Bactericide for preventing and treating plant take-all disease | MONSANTO CO (US) | 1994-04-13 | — | — | CN | disclosed |
| CN-1022832-C | Preparation of 3-substituted-2-oxindole derivatives | PFIZER (US) | 1993-11-24 | — | — | CN | disclosed |
| CN-1046525-A | 3-SUBSTITUTED-2-OXINDOLE DERIVATIVES | PFIZER (US) | 1990-10-31 | — | — | CN | disclosed |