SCHEMBL4489372

SCHEMBL4489372

O=COc1ccc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4570687 0.73
SCHEMBL1698929 0.73
SCHEMBL28967675 0.71 MAPT (0.34)
SCHEMBL621820 0.69
SCHEMBL12542106 0.68 DAO (0.46)
SCHEMBL14227642 0.68 MAPK1 (0.40)
SCHEMBL12215731 0.68 TSHR (0.42)
SCHEMBL10636900 0.67 MAPT (0.39)
SCHEMBL6354512 0.67 PLAU (0.40)
SCHEMBL2567583 0.67 DAO (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108864326-A Photocurable composition and its application 湖北固润科技股份有限公司 2018-11-23 CN disclosed
CN-108864136-A 3,4- ethylenedioxy thiophene derivative and its preparation method and application 湖北固润科技股份有限公司 2018-11-23 CN disclosed
CN-106565664-A Indeno[1,2-b]fluorene unit-based A-D-A conjugate micro-molecule, and application thereof in photoelectric devices 华南理工大学 2017-04-19 CN disclosed
CN-101926017-B Solution processable organic semiconductors based on anthracene 3M INNOVATIVE PROPERTIES CO 2013-09-25 CN disclosed
CN-101111483-B IGF-1R inhibitors KYOWA HAKKO KIRIN CO.,LTD. (JP) 2011-12-14 CN disclosed
CN-102076681-A Substituted gamma-lactams as therapeutic agents ALLERGAN INC 2011-05-25 CN disclosed
CN-101014580-B Morpholine compound MITSUBISHI PHARMA CORP 2011-05-04 CN disclosed
CN-101926017-A Solution processable organic semiconductors based on anthracene 3M INNOVATIVE PROPERTIES CO 2010-12-22 CN disclosed
CN-101842362-A Benzothiazole compounds INST MEDICAL W & E HALL 2010-09-22 CN disclosed
US-7498405-B2 Halogen-substituted thienyl compounds GENESOFT PHARMACEUTICALS, INC. (US) 2009-03-03 US disclosed
CN-100348196-C Benzotriaza * as gastrin and cholecystokinin receptor ligands BLACK JAMES FOUNDATION (GB) 2007-11-14 CN disclosed
CN-101014580-A Morpholine compound MITSUBISHI PHARMA CORP (JP) 2007-08-08 CN disclosed
US-20060287247-A1 Binds nucleic acids; microbiocides for Grampositive infections and drug resistance bacteria GENESOFT PHARMACEUTICALS, INC. (US) 2006-12-21 US disclosed
US-7122626-B2 Halogen-substitued thienyl compounds GENESOFT PHARMCEUTICALS, INC. (US) 2006-10-17 US disclosed
CN-1585643-A Benzotriazepines as gastrin and cholecystokinin receptor ligands BLACK JAMES FOUNDATION (GB) 2005-02-23 CN disclosed
US-20030130198-A1 Halogen-substitued thienyl compounds GENESOFT, INC. (US) 2003-07-10 US disclosed
WO-2002088119-A1 HALOGEN-SUBSTITUTED THIENYL COMPOUNDS GENESOFT PHARMACEUTICALS, INC (US) 2002-11-07 WO disclosed
CN-1233180-A Treatment of the common cold or allergic rhinitis LILLY CO ELI (US) 1999-10-27 CN disclosed
CN-1022832-C Preparation of 3-substituted-2-oxindole derivatives PFIZER (US) 1993-11-24 CN disclosed
CN-1046525-A 3-SUBSTITUTED-2-OXINDOLE DERIVATIVES PFIZER (US) 1990-10-31 CN disclosed