Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16999940 | 0.88 | ESR1 (0.35) | ESR1ESR2PTPN1ALOX15ALOX12 | |
| SCHEMBL16999939 | 0.81 | CYP3A4 (0.42) | ESR1ESR2PTPN1 | |
| SCHEMBL16999930 | 0.81 | TUBB4A (0.43) | PTPN1 | |
| SCHEMBL16999929 | 0.81 | ESR2 (0.34) | ESR1ESR2PTPN1ALOX15ALOX12 | |
| SCHEMBL2731372 | 0.80 | HTR2A (0.34) | ESR1ESR2PTPN1 | |
| SCHEMBL15953600 | 0.80 | HTR2A (0.34) | ESR1ESR2PTPN1 | |
| SCHEMBL10098029 | 0.80 | HTR2A (0.34) | ESR1ESR2PTPN1 | |
| SCHEMBL30362760 | 0.80 | HTR2A (0.34) | ESR1ESR2PTPN1 | |
| SCHEMBL18895899 | 0.77 | KDM1A (0.41) | PTPN1ALOX15ALOX12 | |
| SCHEMBL10098035 | 0.77 | KDM1A (0.41) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2953938-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | Novogen Ltd. (AU) | 2015-12-16 | — | — | EP | disclosed |
| WO-2015117202-A1 | FUNCTIONALISED BENZOPYRAN COMPOUNDS AND USE THEREOF | NOVOGEN LIMITED (AU) | 2015-08-13 | — | — | WO | disclosed |