⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20702483 | 0.77 | — | — | |
| SCHEMBL13743019 | 0.75 | — | — | |
| SCHEMBL153229 | 0.74 | — | — | |
| SCHEMBL29054509 | 0.73 | — | — | |
| SCHEMBL30012928 | 0.73 | — | — | |
| SCHEMBL17816480 | 0.71 | MANBA (0.31) | — | |
| SCHEMBL21164150 | 0.71 | MANBA (0.31) | — | |
| SCHEMBL27485921 | 0.71 | — | — | |
| SCHEMBL13063745 | 0.71 | MANBA (0.31) | — | |
| SCHEMBL27499596 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102215-A2 | 4'-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF INFLUENZA RNA REPLICATION | Riboscience LLC (US) | 2016-12-14 | — | — | EP | disclosed |
| WO-2015120237-A2 | 4'-DIFLUOROMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES AS INHIBITORS OF INFLUENZA RNA REPLICATION | RIBOSCIENCE LLC (US) | 2015-08-13 | — | — | WO | disclosed |