Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.76 |
| ▸ | NT5E | P21589 | 2/20 | 0.76 |
| ▸ | TOP2A | P11388 | 2/20 | 0.76 |
| ▸ | RELA | Q04206 | 1/20 | 0.76 |
| ▸ | SLC10A1 | Q14973 | 2/20 | 0.70 |
| ▸ | ALB | P02768 | 2/20 | 0.69 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.69 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | GLI1 | P08151 | 1/20 | 0.69 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.69 |
| ▸ | DPP4 | P27487 | 1/20 | 0.69 |
| ▸ | RORC | P51449 | 1/20 | 0.69 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.69 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.69 |
| ▸ | CA9 | Q16790 | 4/20 | 0.67 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214201 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL13573802 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL15120375 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL16983599 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL2733084 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL13098063 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL6112842 | 1.00 | PTPN1 (0.76) | PTPN1USP2LMNAHIF1ANT5E | |
| Water SCHEMBL8586171 | 0.99 | PTPN1 (0.75) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL210109 | 0.93 | PTPN1 (0.73) | PTPN1USP2LMNAHIF1ANT5E | |
| SCHEMBL5956480 | 0.92 | PTPN1 (0.72) | PTPN1USP2LMNAHIF1ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102685-B2 | Derivatives of betulin | GLAXOSMITHKLINE LLC (US) | 2015-08-11 | — | — | US | disclosed |
| US-9102685-B2 | Derivatives of betulin | GLAXOSMITHKLINE LLC (US) | 2015-08-11 | — | — | US | disclosed |