Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906991 | 0.81 | PDGFRB (0.40) | PDGFRBPDGFRAACHEALDH1A1MAPT | |
| SCHEMBL12074762 | 0.80 | PDE10A (0.43) | PDGFRBPDGFRAPDE10AACHEALDH1A1 | |
| SCHEMBL12074882 | 0.74 | PDGFRB (0.52) | PDGFRBPDGFRAPDE10AALDH1A1MAPT | |
| SCHEMBL14906837 | 0.72 | CSNK1D (0.42) | PDE10AALDH1A1 | |
| SCHEMBL14903970 | 0.71 | PDE10A (0.40) | PDE10AALDH1A1GLAACACA | |
| SCHEMBL16994469 | 0.69 | PTAFR (0.38) | PDGFRBPDGFRAPDE10AACHEALDH1A1 | |
| SCHEMBL12074199 | 0.67 | TLR9 (0.46) | PDGFRBPDGFRASLC2A1 | |
| SCHEMBL12075017 | 0.66 | PDGFRB (0.67) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12074886 | 0.66 | SLC2A1 (0.57) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL12074196 | 0.66 | PDGFRB (0.51) | PDGFRBPDGFRAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |