Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14906941 | 0.72 | SRD5A1 (0.36) | SRD5A1SRD5A2MTNR1AMTNR1BACHE | |
| SCHEMBL16994470 | 0.69 | PDGFRB (0.40) | PDGFRBPDGFRAALDH1A1GLAGAA | |
| SCHEMBL12074764 | 0.68 | CCNE1 (0.43) | CYP11B1CYP11B2CCNE1CDK2MAPK8 | |
| SCHEMBL12070662 | 0.64 | PTAFR (0.51) | PTAFRPDGFRBPDGFRAALDH1A1MAPT | |
| SCHEMBL12075017 | 0.63 | PDGFRB (0.67) | PDGFRBPDGFRAALDH1A1GLAGAA | |
| SCHEMBL14903985 | 0.62 | MTNR1A (0.33) | CYP11B1CYP11B2MTNR1AMTNR1B | |
| SCHEMBL12074762 | 0.61 | PDE10A (0.43) | PDGFRBPDGFRACYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL31444727 | 0.60 | MAPT (0.42) | PTAFRCYP11B1CYP11B2ALDH1A1GAA | |
| SCHEMBL12074885 | 0.57 | PDGFRB (0.94) | PDGFRBPDGFRAALDH1A1GLAGAA | |
| SCHEMBL1905594 | 0.57 | KDR (0.45) | PDGFRBPDGFRAMAPTSYKPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102617-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2015-08-11 | — | — | US | disclosed |