Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753666 | 0.81 | ESR1 (0.50) | SLC6A2SLC6A4SLC6A3OPRM1MEN1 | |
| SCHEMBL6710551 | 0.81 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL10771729 | 0.81 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3OPRM1MEN1 | |
| SCHEMBL13109242 | 0.81 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3OPRM1MEN1 | |
| Hydrochloric Acid SCHEMBL30838758 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL27620865 | 0.79 | PKM (0.49) | SLC6A2SLC6A4SLC6A3OPRM1MEN1 | |
| SCHEMBL27980935 | 0.72 | MEN1 (0.40) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL28137448 | 0.72 | ESR1 (0.46) | SLC6A2SLC6A4SLC6A3OPRM1KMT2A | |
| SCHEMBL36553 | 0.71 | ESR1 (0.44) | KMT2AESR1ESR2PDCD1CD274 | |
| Cyclopropane SCHEMBL16500003 | 0.71 | ESR1 (0.44) | KMT2AESR1ESR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120087986-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING DESVENLAFAXINE | DR. REDDY'S LABORATORIES, INC. | 2012-04-12 | — | — | US | disclosed |
| US-20120087986-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING DESVENLAFAXINE | DR. REDDY'S LABORATORIES, INC. | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120087986-A1 | PHARMACEUTICAL FORMULATIONS COMPRISING DESVENLAFAXINE | SLC6A2, SLC6A4, VGF | SLC6A2 1/4885SLC6A4 2/4885SLC6A3 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.